Cardiovascular Disease (CVD) is the leading cause of death in the European Union accounting for 1.9 million deaths, i.e. 40% of all deaths in the EU each year. Despite costs of almost €196 billion per year, CVD can be successfully treated and managed – if detected early. The goal of the «PHOCNOSIS» project is the development and pre-clinical validation of a nanotechnology-based, handheld point-of-care testing (POCT) and analysis procedure and device, for fast and early diagnosis of cardiovascular diseases (CVD).